Urusei Yatsura: Terror of Girly-Eyes Measles 1991 うる星やつら: 乙女ばしかの恐怖

Ten gives Ataru an alien disease, the contagious "Girl Measles," (which makes the victim's eyes turn big and twinkly, like the eyes of young girls in much of manga and anime), and when Ataru's girl-hunting spreads the virus all over Tomobiki Town, chaos ensues!